A 15-year-old male patient came to our attention for the appearance of a large mass in the right axilla for about 4 months. In the anamnesis, a first surgical stage of open exploration is reported, which disproved the suspicion of lymphadenopathy. Following preparatory investigations, a diagnosis of suspected schwannoma of the median nerve was attributed, confirmed operatively and by histological examination. The post-operative follow-up was uneventful.